Some 387 people in the UK have been charged with terrorism offences since September 2001, John Reid is to say.
Among those, 214 have been convicted and 98 are still due to go on trial.
The figures will be announced by the home secretary in a speech urging UK businesses to join the government in the "long struggle" against terrorism.
Public, private and voluntary sectors can all help in developing new ways and technologies to defeat the "terrorist menace", he will say.
Mr Reid, who will be addressing a technology conference in central London, will tell business it plays a vital role in creating the security and resilience needed to defeat terrorists.
He is also expected to announce that a new "innovation" forum will be set up to encourage working alongside the government.
Mr Reid is expected to say: "[The terrorism] threat will be enduring - the struggle will be long and wide and deep. And so, therefore, must be our response.
"Of course it will be multi-faceted. But it is vital that our enterprises sustain the delivery of innovation at a pace that outstrips our adversaries."
He will say that both the government and its partners need to be "resilient" as well as innovative in the fight against terrorists.
The figures contained in his speech cover the period from 9 September 2001 to 30 September this year.